We are happy to announce the release of ADDIS v1.12. This new release introduces BRAT framework benefit-risk assessment and several improvements in performance and usability.
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News
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ADDIS v1.12 released2012-02-22
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New publication
Our manuscript "ADDIS: a decision support system for evidence-based medicine" has been accepted for publication in the Decision Support Systems special issue on "Modeling for Better Healthcare". The paper describes the ADDIS system as such, placing it in the context of clinical development and regulatory assessment. The paper details the data model as well as the evidence synthesis and decision modeling that is supported by ADDIS.
2012-02-16 -
GeMTC 0.10.1 released
This new version of GeMTC adresses several small bugs.
2011-02-08 -
ADDIS v1.10.1 bugfix release
ADDIS v1.10.1 is a bugfix release. ADDIS 1.10 introduced a nasty problem that potentially corrupts your data files, so we urge everyone using v1.10 to upgrade immediately to 1.10.1 (see the linked page for more details).
2011-11-28 -
ADDIS v1.10 released
We are happy to announce the release of ADDIS v1.10. This new release introduces a graphical installer, double-click opening of data files and additional study design features.
2011-11-04 -
GeMTC 0.10 released
This new version of GeMTC adds a new graphical user interface (GUI) and the ability to generate WinBUGS/OpenBUGS models.
2011-09-23 -
Two new publications
Our manuscript "Multi-criteria benefit-risk assessment using network meta-analysis" has been accepted by the Journal of Clinical Epidemiology. The paper details the evidence-synthesis based SMAA benefit-risk model implemented in ADDIS since v0.10 (and refined in subsequent versions).
The second paper, "Algorithmic Parameterization of Mixed Treatment Comparisons", will appear as an open access article in Statistics and Computing. It discusses how inconsistency models for network meta-analysis can be generated automatically, and so it describes functionality included in both ADDIS and our MTC software.
See our publications page for details on these and other publications.
2011-09-13 -
ADDIS v1.8 released
We are happy to announce the release of ADDIS v1.8. This new release introduces additional study design modeling features through a more advanced data model.
2011-07-01 -
ADDIS v1.6.2 released
The ADDIS v1.6.2 release fixes a bug that we unfortunately introduced with the improvements for 1.6.1. The bug was only apparent on some computers, but not on ours.
2011-06-10 -
ADDIS v1.6.1 released
The ADDIS v1.6.1 release brings performance improvements and bugfixes for the network meta-analysis functionality.
2011-06-05 -
ADDIS v1.6 released
The ADDIS v1.6 release aims to solidify the current functionality and includes many bug fixes and usability enhancements. Moreover, internal improvements have been made to support faster future evolution, such as the introduction of a formal data representation based on XML schema.
2011-04-15 -
MTC v0.8 released
MTC v0.8 brings the generation of JAGS models back up-to-date with the functionality in ADDIS. Most importantly, node-splitting models can now be generated. In addition, multiple chains with overdispersed starting values are generated and some R code is provided to aid in data analysis. See our MTC page for information and downloads.
2011-01-17 -
Benefit-risk model published
Our manuscript "A stochastic multicriteria model for evidence-based decision making in drug benefit-risk analysis" has been accepted by Statistics in Medicine. The paper details the "single-study SMAA" benefit-risk model implemented in ADDIS since v1.2.
See our publications page for details on this and other publications.
2010-12-21 -
ADDIS v1.4 released
We are happy to announce the release of ADDIS v1.4. The new release brings enhancements to network meta-analysis that make it possible to do a full analysis in ADDIS. An additional benefit-risk model, Lynd and O'Brien analysis, has been added. Finally, pair-wise meta-analyses can now be corrected for zeroes.
2010-12-20 -
ADDIS v1.2.1 released
ADDIS v1.2.1 has been released to address a bug that prevented domain object from being deleted or edited.
2010-10-21 -
ADDIS v1.2 released
We are happy to announce the release of ADDIS v1.2. We deviate from our normal 3-monthly schedule to introduce an important feature: benefit-risk analysis based on a single study.
2010-09-27 -
ADDIS v1.0 released
We are happy to announce the release of ADDIS v1.0. In this release, we have refined usability and stability and also bring some new features such as editing of studies.
2010-09-09 -
ADDIS project status
Over a year of ADDIS development is summarized in the ADDIS project update. It summarizes the progress made in the past year, outlines future goals and gives an update on the personnel situation.
Also note that we recently updated our publications page with a number of new posters, presentation slides and Jing Zhao's master thesis.
2010-06-22 -
ADDIS v0.10 released
We are happy to announce the release of ADDIS v0.10. In this release, we build upon meta-analysis and network meta-analysis, to perform multi-criteria benefit-risk analysis of alternative treatment options.
2010-06-21 -
MTC v0.4
We are happy to announce MTC v0.4, the second release of our library for Mixed Treatment Comparison (network meta-analysis) model generation. It is the first software of it's kind, and can be used to generate correct parametrizations of (in)consistency models for both dichotomous and continuous outcomes.
2009-06-11 -
MTC v0.2, ADDIS v0.8.1 released
We are happy to announce MTC v0.2, the first release of our library for Mixed Treatment Comparison (network meta-analysis) model generation. It is the first software of it's kind, and can be used to generate correct parametrizations of (in)consistency models for both dichotomous and continuous outcomes.
In addition, ADDIS v0.8.1 was released, now using the official release of the MTC library. The new version brings speed and memory usage improvements to network meta-analysis, and various improvements to the user interface.
2010-05-07 -
ADDIS v0.8 released
We are happy to announce ADDIS v0.8. ADDIS v0.8 introduces network meta-analysis, making ADDIS the first software to offer automatic model generation for network meta-analysis. In addition, your ADDIS data can now be saved as XML, ensuring that you can still use it in future versions of ADDIS.
2010-04-27 -
ADDIS v0.6.1 released
We are happy to announce ADDIS v0.6.1. ADDIS v0.6.1 provides one additional feature requested by a colleague: the ability to dynamically add new types of population characteristic.
2010-02-16 -
ADDIS v0.6 released
We are happy to announce the third release of ADDIS, version 0.6. ADDIS v0.6 provides better data input facilities and import from ClinicalTrials.gov.
2010-02-12 -
New page: Research
A new page outlining our research was added to the website. It explains the context of our project, lists our research interests and gives relevant literature. In addition, the list of publications was updated.
2010-01-05 -
Personnel changes
A replacement occurred in our software development team. Maarten Jacobs' contract ended, and he left in order to pursue a PhD. He has been replaced by Hanno Koeslag starting today.
2010-01-04 -
ADDIS v0.4.1 released
ADDIS v0.4.1 is the first maintanance release of ADDIS version 0.4. This release fixes two minor issues, and we recommend upgrading to this version if you are using 0.4.
2009-12-08 -
ADDIS v0.4 released
We are happy to announce the second release of ADDIS, version 0.4. ADDIS v0.4 provides a toolbox for random effects meta-analysis.
2009-11-26 -
Status update
The release planning meeting for ADDIS v0.4 took place on 3 September, 2009. ADDIS v0.4 development will be focussed on expanding our toolkit for meta-analysis.
In addition, we are hiring two part-time programmers to speed development of the system. It is still uncertain how this will affect our schedule.
2009-10-13 -
ADDIS v0.2 released
We are happy to announce the first release of ADDIS, version 0.2. This is the first, experimental, version of ADDIS released to the general public.
2009-06-30 -
drugis.org launched
drugis.org has been launched to promote the visible and open development of ADDIS, our proof-of-concept information system for the storage, retrieval, (meta-)analysis and benefit-risk assessment of clinical trials data.
The website will contain a description of our software and development process, as well as source code, nightly builds and released versions of our software.
2009-06-11